0000001 - Document - Cover link:presentationLink link:calculationLink link:definitionLink 9952151 - Statement - Condensed Consolidated Balance Sheets link:presentationLink link:calculationLink link:definitionLink 9952152 - Statement - Condensed Consolidated Balance Sheets (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952153 - Statement - Condensed Consolidated Statements of Comprehensive Income (Loss) link:presentationLink link:calculationLink link:definitionLink 9952154 - Statement - Condensed Consolidated Statements of Cash Flows link:presentationLink link:calculationLink link:definitionLink 9952154 - Statement - Condensed Consolidated Statements of Cash Flows link:presentationLink link:calculationLink link:definitionLink 9952155 - Statement - Condensed Consolidated Statements of Stockholders' Deficit link:presentationLink link:calculationLink link:definitionLink 9952156 - Disclosure - Significant Accounting Policies and Concentrations of Risk link:presentationLink link:calculationLink link:definitionLink 9952157 - 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Disclosure - Collaborative and Other Relationships link:presentationLink link:calculationLink link:definitionLink 9952168 - Disclosure - Segment Information link:presentationLink link:calculationLink link:definitionLink 9952169 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 9952170 - Disclosure - Net Income (Loss) Per Share link:presentationLink link:calculationLink link:definitionLink 9952171 - Disclosure - Subsequent Event link:presentationLink link:calculationLink link:definitionLink 9955511 - Disclosure - Significant Accounting Policies and Concentrations of Risk (Policies) link:presentationLink link:calculationLink link:definitionLink 9955512 - Disclosure - Significant Accounting Policies and Concentrations of Risk (Tables) link:presentationLink link:calculationLink link:definitionLink 9955513 - Disclosure - Assets and Liabilities Held For Sale (Tables) link:presentationLink link:calculationLink link:definitionLink 9955514 - 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Disclosure - Significant Accounting Policies and Concentrations of Risk (Details) link:presentationLink link:calculationLink link:definitionLink 9955524 - Disclosure - Significant Accounting Policies and Concentrations of Risk - Summary of Revenues (Details) link:presentationLink link:calculationLink link:definitionLink 9955525 - Disclosure - Assets and Liabilities Held For Sale (Details) link:presentationLink link:calculationLink link:definitionLink 9955526 - Disclosure - Assets and Liabilities Held For Sale - Schedule of Assets Held For Sale (Details) link:presentationLink link:calculationLink link:definitionLink 9955527 - Disclosure - Revenue (Details) link:presentationLink link:calculationLink link:definitionLink 9955528 - Disclosure - Investments - Fair Value, Recurring Basis (Details) link:presentationLink link:calculationLink link:definitionLink 9955529 - Disclosure - Investments - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955530 - Disclosure - Investments- Fair Value of the Company's Investments by Type (Details) link:presentationLink link:calculationLink link:definitionLink 9955531 - Disclosure - Investments - Schedule of Maturity of Investments (Details) link:presentationLink link:calculationLink link:definitionLink 9955532 - Disclosure - Trade Receivables (Details Textual) link:presentationLink link:calculationLink link:definitionLink 9955533 - Disclosure - Inventory - Summary of Inventories (Details) link:presentationLink link:calculationLink link:definitionLink 9955534 - Disclosure - Inventory (Details) link:presentationLink link:calculationLink link:definitionLink 9955535 - Disclosure - Royalty Financing Obligations (Details Textual) link:presentationLink link:calculationLink link:definitionLink 9955536 - Disclosure - Royalty Financing Obligations - Schedule of Royalty Financing Obligations (Details) link:presentationLink link:calculationLink link:definitionLink 9955537 - Disclosure - Debt (Details) link:presentationLink link:calculationLink link:definitionLink 9955538 - Disclosure - Lease Obligations (Details Textual) link:presentationLink link:calculationLink link:definitionLink 9955539 - Disclosure - Lease Obligations - Aggregate Lease Expense Under Operating Leases (Details) link:presentationLink link:calculationLink link:definitionLink 9955540 - Disclosure - Lease Obligations - Other Supplemental Information Related to Leases (Details) link:presentationLink link:calculationLink link:definitionLink 9955541 - Disclosure - Lease Obligations - Balance Sheets of the Company's Operating Leases (Details) link:presentationLink link:calculationLink link:definitionLink 9955542 - Disclosure - Lease Obligations - Balance Sheets of the Company's Finance Leases (Details) link:presentationLink link:calculationLink link:definitionLink 9955543 - Disclosure - Lease Obligations - Maturities of Lease Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955543 - Disclosure - Lease Obligations - Maturities of Lease Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955544 - Disclosure - Lease Obligations - Supplemental Cash Flows (Details) link:presentationLink link:calculationLink link:definitionLink 9955545 - Disclosure - Stockholders' Equity - Shares Reserved for Future Issuance (Details) link:presentationLink link:calculationLink link:definitionLink 9955546 - Disclosure - Stock-based Compensation (Details Textual) link:presentationLink link:calculationLink link:definitionLink 9955547 - Disclosure - Stock-based Compensation - Share-Based Compensation (Details) link:presentationLink link:calculationLink link:definitionLink 9955548 - Disclosure - Stock-based Compensation - Option Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955549 - Disclosure - Stock-based Compensation - Restricted Stock Unit Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955550 - Disclosure - Stock-based Compensation - Weighted Average Assumptions for Stock Option Awards Granted to Employees and Directors Under the Plans (Details) link:presentationLink link:calculationLink link:definitionLink 9955551 - 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