Term B And C Loan Term B And C Loan [Member] Term B And C Loan Lessee, Operating Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract] Lessee, Operating Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract] Options, aggregate intrinsic value Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term Adjustments to reconcile net loss to net cash used in operating activities: Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Work-in-process Inventory, Work in Process, Gross Statistical Measurement [Domain] Statistical Measurement [Domain] Gross Unrealized Losses Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax Aggregate Lease Expense Under Operating Leases Lease, Cost [Table Text Block] Cover [Abstract] Thereafter Lessee Operating Lease Liability To Be Paid After Year Four Amount of lessee's undiscounted obligation for lease payment for operating lease due after fourth fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach). Decrease in cash, cash equivalents and restricted cash Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Maturities of Operating Lease Liabilities Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block] Trading Symbol Trading Symbol Maturing after one year but less than two years Maturing After One Year And Before Two Years Amount of investment in debt securities maturing after one year through two years. Thereafter Finance Lease, Liability, to be Paid, After Year Four Finance Lease, Liability, to be Paid, After Year Four All Trading Arrangements All Trading Arrangements [Member] Incentive Plan Incentive Plan [Member] Represents Incentive Plan. MidCap Financial Services, LLC MidCap Financial Services, LLC [Member] Represents MidCap Financial Services, LLC entity. Compensation Actually Paid vs. Net Income Compensation Actually Paid vs. Net Income [Text Block] Non-NEOs Non-NEOs [Member] Collaborative and other revenues Collaborative and Other Research and Development [Member] Information pertaining to Collaborative and other research and development. Rule 10b5-1 Arrangement Adopted Rule 10b5-1 Arrangement Adopted [Flag] Awards Close in Time to MNPI Disclosures Awards Close in Time to MNPI Disclosures [Table] Billed Billed Revenues [Member] Pay vs Performance Disclosure [Line Items] Peer Group Total Shareholder Return Amount Peer Group Total Shareholder Return Amount Net Loss Per Share Earnings Per Share, Policy [Policy Text Block] Inventory Inventory, Policy [Policy Text Block] Non-Rule 10b5-1 Arrangement Adopted Non-Rule 10b5-1 Arrangement Adopted [Flag] Debt instrument, LIBOR cap Debt Instrument Libor Cap Maximum LIBOR interest rate for debt instrument. ESPP Employee Stock Purchase Plan [Member] Employee stock purchase plan, (ESPP). Restructuring and Related Activities [Abstract] Unrealized gain on available for sale investments OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax Award Timing Disclosures [Line Items] Annual Net Sales Over $550,000 Annual Net Sales Over $550,000 [Member] Represents annual net sales over $550,000. Other Performance Measure, Amount Other Performance Measure, Amount Lease Obligations Lessee, Operating Leases [Text Block] Common stock, shares, outstanding (in shares) Common stock, shares outstanding, beginning balance (in shares) Common stock, shares outstanding, ending balance (in shares) Common Stock, Shares, Outstanding Restricted Cash and Cash Equivalents [Axis] Restricted Cash and Cash Equivalents [Axis] Number of common stock shares available for purchase (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant Operating lease liabilities Operating Lease, Liability, Noncurrent Athyrium Athyrium [Member] Represents Athyrium Opportunities III Co-Invest 1 LP (“Athyrium”). Investments, All Other Investments [Abstract] Interest on lease liabilities Finance Lease, Interest Expense Geographic Distribution [Axis] Geographic Distribution [Axis] Revenue from Contract with Customer [Abstract] Royalty purchase agreement, royalties, percentage of purchase price Royalty Purchase Agreement Royalties Percentage Of Purchase Price The percentage of the purchase price under the royalty purchase agreement. RAPIVAB RAPIVAB [Member] Represents RAPIVAB product. 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PIK Interest Payment is Made PIK Interest Payment is Made [Member] Represents PIK interest payment is made. BCX10013 BCX10013 [Member] BCX10013 Restructuring and Related Costs Restructuring and Related Costs [Table Text Block] Payment of debt issuance costs on Pharmakon Tranche A term loan Payments of Debt Issuance Costs Tabular List, Table Tabular List [Table Text Block] Potential payment if milestone reached Potential Milestone Payments Payable If Regulatory Approval Before Milestone Potential Milestone Payments Payable If Regulatory Approval Before Milestone Significant Unobservable Inputs (Level 3) Fair Value, Inputs, Level 3 [Member] Annual global net sales License Agreement, Annual Global Net Sales License Agreement, Annual Global Net Sales Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Debt instrument, LIBOR floor Debt Instrument Libor Floor Minimum LIBOR interest rate for debt instrument. Significant Accounting Policies and Concentrations of Risk [Table] Significant Accounting Policies and Concentrations of Risk [Table] Significant Accounting Policies and Concentrations of Risk Total receivables Receivables, Net, Current Long-term investment maturity, minimum (in years) Long term Investment Maturity Minimum Represents long term investment maturity minimum. Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table [Member] Term Loan Tranche C Term Loan Tranche C [Member] Term Loan Tranche C Employee stock purchase plan sales, net (in shares) Stock Issued During Period, Shares, Employee Stock Purchase Plans Accrued expenses Accrued Liabilities, Current Antidilutive securities excluded from computation of earnings per share, amount (in shares) Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Operating lease expense Operating Lease, Expense Less imputed interest Finance Lease, Liability, Undiscounted Excess Amount Payments for restructuring Payments for Restructuring Credit Facility [Domain] Credit Facility [Domain] Cost of Product Sales Cost of Goods and Service [Policy Text Block] Trade Receivables [Table] Accounts and Financing Receivables [Table] Total unrecognized compensation expense related to non-vested stock options and RSU awards Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount Royalty purchase agreement, royalties, percentage of annual net sales, based on reduction in sales Royalty Purchase Agreement Royalties Percentage Of Annual Net Sales Based On Reduction In Sales he percentage of annual net sales of royalties to be paid under the royalty purchase agreement if sales are less than specified. Current assets: Assets, Current [Abstract] Withholding taxes paid on stock-based awards Payment, Tax Withholding, Share-Based Payment Arrangement Inventory Inventory Disclosure [Text Block] Forgone Recovery due to Disqualification of Tax Benefits, Amount Forgone Recovery due to Disqualification of Tax Benefits, Amount Product and Service [Domain] Product and Service [Domain] Outstanding stock options Share-Based Payment Arrangement, Option [Member] Restricted stock units, vested in period, weighted average grant date fair value (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value 2025 Lessee, Operating Lease, Liability, to be Paid, Year One Net comprehensive loss Comprehensive Income (Loss), Net of Tax, Attributable to Parent Finance leases Finance Lease, Weighted Average Discount Rate, Percent Preferred stock, shares outstanding (in shares) Preferred Stock, Shares Outstanding Repayments of lines of credit Repayments of Lines of Credit Annual Net Sales Between $150,000 and $230,000 Annual Net Sales Between $150,000 and $230,000 [Member] Represents annual net sales between $150,000 and $230,000. Warrants to purchase common stock Warrant [Member] Security Exchange Name Security Exchange Name 2025 Finance Lease, Liability, to be Paid, Year One Paid-in-kind interest Paid-in-Kind Interest Debt instrument, basis spread on variable rate Debt Instrument, Basis Spread on Variable Rate Amortized Cost Debt Securities, Available-for-Sale, Amortized Cost, Excluding Accrued Interest, after Allowance for Credit Loss Award Type [Axis] Award Type [Axis] Number of royalties tiers License Agreement, Royalty Payment, Number of Tiers License Agreement, Royalty Payment, Number of Tiers Collateral for Credit Collateral for Credit [Member] Restricted cash and cash equivalents required to maintain as collateral for a letter of credit. Total inventory Inventory, Gross Weighted average exercise price of stock option awards exercised (in usd per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Restricted Cash Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block] Debt instrument, exit fee, percentage of principal Debt Instrument Exit Fee Percentage of Principal The percentage of principal for exit fee of the debt instrument. Other revenues Other Income From Contract With Customer [Member] Other Income From Contract With Customer Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward] Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward] Property and equipment, net Property, Plant and Equipment, Net Total liabilities Liabilities Weighted average exercise price, stock option awards, exercisable (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price The Company Description of Company [Policy Text Block] The description of company policy. Common stock par value (in usd per share) Common Stock, Par or Stated Value Per Share Forgone Recovery, Explanation of Impracticability Forgone Recovery, Explanation of Impracticability [Text Block] Legal Entity Type of Counterparty [Domain] Legal Entity Type of Counterparty [Domain] Fair Value of the Company's Investments by Type Debt Securities, Available-for-Sale [Table Text Block] Research and development Research and Development Expense Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Foreign Currency Foreign Currency Transactions and Translations Policy [Policy Text Block] Expiration Date Trading Arrangement Expiration Date Term B Loan Term B Loan [Member] Represents term B loan. Trade Receivables Trade Receivables [Text Block] The entire disclosure for trade receivables. Finance lease assets obtained in exchange for finance lease liabilities: Right-of-Use Asset Obtained in Exchange for Finance Lease Liability Cash flows from investing activities: Net Cash Provided by (Used in) Investing Activities [Abstract] Royalty Financing Obligations Royalty Financing Liabilities [Text Block] Royalty monetization. Operating lease liabilities Operating Lease, Liability, Current Total Shareholder Return Amount Total Shareholder Return Amount Common stock, shares, issued (in shares) Common Stock, Shares, Issued Equity Awards Adjustments, Footnote Equity Awards Adjustments, Footnote [Text Block] Summary of Receivables Schedule of Receivables from Collaborations [Table Text Block] Tabular disclosure representing receivables from collaborations. Computer Equipment Computer Equipment [Member] Insider Trading Policies and Procedures Adopted Insider Trading Policies and Procedures Adopted [Flag] Total finance lease expense Financing Lease, Expense Financing Lease, Expense Accounts receivable, after allowance for credit loss, total Accounts Receivable, after Allowance for Credit Loss Exercise of stock options, net (in shares) Options exercised (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Interest Expense, Deferred Financing Costs and Royalty Financing Obligations Interest Expense, Deferred Financing Costs, and Royalty Financing Liabilities [Policy Text Block] Disclosure of accounting policy for interest expense and royalty financing obligation. Debt Instrument [Line Items] Debt Instrument [Line Items] Named Executive Officers, Footnote Named Executive Officers, Footnote [Text Block] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Common stock, shares authorized (in shares) Common Stock, Shares Authorized Basis of Presentation Basis of Accounting, Policy [Policy Text Block] Weighted average shares outstanding, diluted (in shares) Weighted Average Number of Shares Outstanding, Diluted Restructuring costs Restructuring Costs MNPI Disclosure Timed for Compensation Value MNPI Disclosure Timed for Compensation Value [Flag] Long-Term Debt, Type [Axis] Long-Term Debt, Type [Axis] Total stockholders’ deficit Beginning balance Ending balance Equity, Attributable to Parent Operating Lease, Liability [Abstract] Operating Lease, Liability [Abstract] Proceeds from issuance of debt Proceeds from Issuance of Debt Collaborative and Other Relationships Collaborative Arrangement Disclosure [Text Block] Maturing in one year or less Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, Year One Interest expense Interest Expense, Nonoperating 2021 RPI Royalty Agreement 2021 RPI Royalty Agreement [Member] Information on 2021 RPI Royalty Agreement. Number of doses permitted to be procured Maximum Number Of Products Permitted To Be Obtained, Doses Maximum Number Of Products Permitted To Be Obtained, Doses Selling, general and administrative Selling, General and Administrative Expense Other comprehensive income (loss) Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent Trade receivables Accounts Receivable, after Allowance for Credit Loss, Current Performance-based stock options issued in period (in shares) Options, grants in period, gross (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Product sales, net Product [Member] Number of shares of common stock authorized to be purchased (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized Long-term debt, total Long-Term Debt Pension Adjustments Prior Service Cost Pension Adjustments Prior Service Cost [Member] Document Fiscal Period Focus Document Fiscal Period Focus Number of milestone payments License Agreement, Number of Milestone Payments License Agreement, Number of Milestone Payments Annual Net Sales Over $3 Million Annual Net Sales Over $3 Billions [Member] Represents annual net sales over $3 billions. All Executive Categories All Executive Categories [Member] Annual Net Sales Between $350,000 and $550,000 Annual Net Sales Between $350,000 and $550,000 [Member] Represents annual net sales between $350,000 and $550,000. Changed Peer Group, Footnote Changed Peer Group, Footnote [Text Block] Options, exercises in period, intrinsic value Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Assets Assets [Abstract] Expected Dividend Yield Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate Document Type Document Type Effective interest rate Debt Instrument, Interest Rate, Effective Percentage Vesting of restricted stock units Stock Issued During Period, Value, Restricted Stock Award, Gross Pension Benefits Adjustments, Footnote Pension Benefits Adjustments, Footnote [Text Block] After Fourth Anniversary After Fourth Anniversary [Member] Represents after the fourth anniversary. Total Shareholder Return Vs Peer Group Total Shareholder Return Vs Peer Group [Text Block] Vesting of restricted stock units (in shares) Stock Issued During Period, Shares, Restricted Stock Award, Gross Taxes withheld on stock-based awards included in accrued expenses Withholding Taxes Accrued Withholding Taxes Accrued Debt instrument capitalized interest rate Debt Instrument Capitalized Interest Rate Debt Instrument Capitalized Interest Rate Torii Pharmaceutical Co. Torii Pharmaceutical Co. [Member] Information related to Torii Pharmaceutical Co., Ltd. 2027 Finance Lease, Liability, to be Paid, Year Three Cash, cash equivalents and restricted cash at beginning of period Cash, cash equivalents and restricted cash at end of period Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations Options, exercisable, weighted average remaining contractual term (year) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Vested RSU (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Interest expense Interest Expense, Long-Term Debt Risk-Free Interest Rate Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Secured Overnight Financing Rate (SOFR) Overnight Index Swap Rate Secured Overnight Financing Rate (SOFR) Overnight Index Swap Rate [Member] Annual Net Sales Under $350,000 Annual Net Sales Under $350,000 [Member] Represents annual net sales under $350,000. Maximum Maximum [Member] HHS Office of the Administration for Strategic Preparedness and Response HHS Office of the Administration for Strategic Preparedness and Response [Member] HHS Office of the Administration for Strategic Preparedness and Response Equity Valuation Assumption Difference, Footnote Equity Valuation Assumption Difference, Footnote [Text Block] Royalty purchase agreement, royalties, percentage of annual net sales Royalty Purchase Agreement Royalties Percentage Of Annual Net Sales The percentage of annual net sales for royalties to be paid under the royalty purchase agreement. Furniture and Fixtures Furniture and Fixtures [Member] Antidilutive Securities [Axis] Antidilutive Securities [Axis] Accounts payable Accounts Payable, Current Accounting Policies [Abstract] Accounting Policies [Abstract] Revenues Revenues [Abstract] Weighted Average Assumptions for Stock Option Awards Granted to Employees and Directors Under the Plans Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Fair Value Measurements Fair Value Measurement, Policy [Policy Text Block] Current Fiscal Year End Date Current Fiscal Year End Date Less imputed interest Lessee, Operating Lease, Liability, Undiscounted Excess Amount Statistical Measurement [Axis] Statistical Measurement [Axis] PEO Name PEO Name Warrants outstanding (in shares) Class of Warrant or Right, Outstanding Finance lease, right-of-use asset, accumulated amortization Finance Lease, Right-of-Use Asset, Accumulated Amortization Non-Rule 10b5-1 Arrangement Terminated Non-Rule 10b5-1 Arrangement Terminated [Flag] Loss before income taxes Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Non-PEO NEO Average Total Compensation Amount Non-PEO NEO Average Total Compensation Amount Award Type [Domain] Award Type [Domain] Name Outstanding Recovery, Individual Name Disaggregation of Revenue [Line Items] Disaggregation of Revenue [Line Items] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Compensation Actually Paid vs. Company Selected Measure Compensation Actually Paid vs. Company Selected Measure [Text Block] Non-PEO NEO Non-PEO NEO [Member] Advance Royalties [Abstract] Royalty Royalty The amount of royalty expense (reversal of expense) during the period. Additional Paid-in Capital Additional Paid-in Capital [Member] Finance lease liabilities Finance Lease, Liability, Noncurrent Award Timing Predetermined Award Timing Predetermined [Flag] Annual Net Sales Between $1.5 and $3 Millions Annual Net Sales Between $1.5 and $3 Billions [Member] Represents annual net sales between $1.5 and $3 billions. Recently Adopted Accounting Pronouncements And New Accounting Pronouncements Not Yet Adopted New Accounting Pronouncements, Policy [Policy Text Block] Forecast Forecast [Member] Diluted net loss per common share (in usd per share) Earnings Per Share, Diluted 2028 Finance Lease, Liability, to be Paid, Year Four Counterparty Name [Domain] Counterparty Name [Domain] Name Measure Name Entity Interactive Data Current Entity Interactive Data Current Type of Restructuring [Domain] Type of Restructuring [Domain] Deferred revenue Increase (Decrease) in Contract with Customer, Liability Restatement does not require Recovery Restatement Does Not Require Recovery [Text Block] Cash paid for taxes Income Taxes Paid Preferred stock, shares issued (in shares) Preferred Stock, Shares Issued Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block] Disaggregation of Revenue [Table] Disaggregation of Revenue [Table] Employee Severance Employee Severance [Member] Statement of Financial Position [Abstract] Statement of Financial Position [Abstract] Workforce Reduction Restructuring and Related Activities Disclosure [Text Block] Receivables Increase (Decrease) in Receivables Stock-based compensation expense Share-Based Payment Arrangement, Noncash Expense Repayment of Athyrium secured term loans principal Repayments of Secured Debt Income tax expense Income Tax Expense (Benefit) Investments Debt Securities, Available-for-Sale, Current Options cancelled or forfeited (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period Supplemental Cash Flow Information [Abstract] Supplemental Cash Flow Information [Abstract] Payments for restructuring, net Payments For Restructuring, Net Payments For Restructuring, Net Weighted-average term to recognize non-vested stock options and RSU awards Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Inventory obsolescence Inventory Write-down Schedule of the Maturity of Investments Debt Securities, Held-to-Maturity [Table Text Block] Net cash provided by (used in) investing activities Net Cash Provided by (Used in) Investing Activities Income (loss) from operations Operating Income (Loss) After Third Anniversary After Third Anniversary [Member] After Third Anniversary Variable Rate [Domain] Variable Rate [Domain] 2024 (remaining) Finance Lease, Liability, to be Paid, Remainder of Fiscal Year Total liabilities and stockholders’ deficit Liabilities and Equity Subsequent Event Subsequent Events [Text Block] Rule 10b5-1 Arrangement Terminated Rule 10b5-1 Arrangement Terminated [Flag] All Adjustments to Compensation All Adjustments to Compensation [Member] Clearside Biomedical, Inc. Clearside Biomedical, Inc. [Member] Clearside Biomedical, Inc. Fair Value Hierarchy and NAV [Axis] Fair Value Hierarchy and NAV [Axis] Prepaid expenses and other assets Increase (Decrease) in Prepaid Expense and Other Assets Additional paid-in capital Additional Paid in Capital Debt instrument, commitment fee percentage Debt Instrument Commitment Fee Percentage The commitment fee percentage of the debt instrument. 2026 Finance Lease, Liability, to be Paid, Year Two Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity [Table Text Block] Royalty rate if maintains sakigake designation Royalty Rate If Maintains Sakigake Designation The percent of net sales that the company will receive if berotralstat maintains its Sakigake designation during the PMDA review. Operating lease assets obtained in exchange for operating lease liabilities: Right-of-Use Asset Obtained in Exchange for Operating Lease Liability Underlying Security Market Price Change Underlying Security Market Price Change, Percent Scenario [Domain] Scenario [Domain] Individual: Individual [Axis] Shares withheld for taxes for vesting of restricted stock units Share-Based Payment Arrangement, Decrease for Tax Withholding Obligation Accumulated Other Comprehensive Income AOCI Attributable to Parent [Member] Retirement Policy Retirement Policy [Policy Text Block] Retirement Policy Expected life in years Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Inventory, net Inventory, Net Obligations of U.S. Government and its agencies US Government Agencies Debt Securities [Member] Long-Term Debt, Type [Domain] Long-Term Debt, Type [Domain] Product and Service [Axis] Product and Service [Axis] Entity Address, State or Province Entity Address, State or Province Statement [Line Items] Statement [Line Items] Erroneous Compensation Analysis Erroneous Compensation Analysis [Text Block] Inducement Plan Inducement Plan [Member] Related to the Inducement Plan. Compensation Actually Paid vs. Total Shareholder Return Compensation Actually Paid vs. Total Shareholder Return [Text Block] Financial Instruments [Domain] Financial Instruments [Domain] Accounts, Notes, Loans and Financing Receivable [Line Items] Accounts, Notes, Loans and Financing Receivable [Line Items] Nonvested RSU weighted average grant date fair value beginning balance (in dollars per share) Nonvested RSU weighted average grant date fair value ending balance (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Liabilities and Stockholders’ Deficit Liabilities and Equity [Abstract] Debt instrument, unamortized discount (premium) and debt issuance costs, net, total Debt Instrument, Unamortized Discount (Premium) and Debt Issuance Costs, Net Minimum Minimum [Member] Restatement Determination Date Restatement Determination Date Number of stock option awards vested and expected to vest (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Operating lease, right-of-use asset, accumulated amortization Operating Lease Right of use Asset Accumulated Amortization Amount of accumulated amortization on lessee's right to use underlying asset under operating lease. Debt instrument, periodic payment Debt Instrument, Periodic Payment Adoption Date Trading Arrangement Adoption Date Pay vs Performance Disclosure Pay vs Performance Disclosure [Table] Exercise of warrants (in shares) Stock Issued During Period, Shares, Warrants Exercised Stock Issued During Period, Shares, Warrants Exercised Schedule of Research and Development Arrangement, Contract to Perform for Others [Table] Research and Development, Contract to Perform for Others [Table] Weighted average exercise price, beginning balance (in usd per share) Weighted average exercise price, ending balance (in usd per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Operating lease assets, net Operating Lease, Right-of-Use Asset Erroneously Awarded Compensation Recovery Erroneously Awarded Compensation Recovery [Table] Options outstanding, beginning balance (in shares) Options outstanding, ending balance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year [Member] Disclosure of Share-Based Compensation Arrangements by Share-Based Payment Award Disclosure of Share-Based Compensation Arrangements by Share-Based Payment Award [Table Text Block] Exercise Price Award Exercise Price Arrangement Duration Trading Arrangement Duration Employee stock purchase plan sales Stock Issued During Period, Value, Employee Stock Purchase Plan Trade Accounts Receivable Trade Accounts Receivable [Member] Exercise of stock options, net Stock Issued During Period, Value, Stock Options Exercised Expenses: Costs and Expenses [Abstract] Restricted cash Restricted Cash and Cash Equivalents, Current Stockholders’ deficit: Equity, Attributable to Parent [Abstract] Restricted stock units, grants in period, weighted average grant date fair value (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Marketable Securities [Table] Marketable Securities [Table] Maximum customary reduction on royalty rate Maximum Customary Reduction On Royalty Rate The maximum percentage of customary reductions allowed on royalty rate. Long-term investments Long-Term Investments Contract value Collaborative Agreement Contract Value Collaborative Agreement Contract Value Income Taxes Income Tax, Policy [Policy Text Block] Peer Group Issuers, Footnote Peer Group Issuers, Footnote [Text Block] Interest income Interest and Other Income Material Terms of Trading Arrangement Material Terms of Trading Arrangement [Text Block] Unbilled Unbilled Revenues [Member] Debt instrument, term Debt Instrument, Term Balance Sheets of the Company's Operating Leases Lessee, Operating Lease, Assets and Liabilities [Table Text Block] Tabular disclosure of the assets and liabilities of the lessee's operating lease. Term A Loan Term A Loan [Member] Represents term A loan. Total Total Finance Lease, Liability All Individuals All Individuals [Member] Debt Instrument, SOFR floor Debt Instrument, Variable Rate floor Debt Instrument, Variable Rate floor Term C Loan Term C Loan [Member] Represents term C loan. PEO PEO [Member] Variable Rate [Axis] Variable Rate [Axis] Maturity period of short term investment (in months) Maturity Period Of Short Term Investment Maturity period of short term investment. Fair value Debt Instrument, Fair Value Disclosure Billing Status, Type [Axis] Billing Status, Type [Axis] Name Trading Arrangement, Individual Name Statement of Stockholders' Equity [Abstract] Statement of Stockholders' Equity [Abstract] Receivables [Abstract] One-time Termination Benefits One-time Termination Benefits [Member] Long-Lived Tangible Asset [Axis] Long-Lived Tangible Asset [Axis] Gross Unrealized Gains Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax Net proceeds from common stock issued under stock-based compensation plans Proceeds, Issuance of Shares, Share-Based Payment Arrangement, Including Option Exercised The 2021 RPI Royalty Purchase Agreement The 2021 RPI Royalty Purchase Agreement [Member] Represents the 2021 RPI Royalty Purchase Agreement. Awards Close in Time to MNPI Disclosures, Table Awards Close in Time to MNPI Disclosures [Table Text Block] OMERS Royalty Agreement OMERS Royalty Agreement [Member] Information on OMERS Royalty Agreement. Lender Name [Axis] Lender Name [Axis] Total shares reserved for future issuance Common Stock, Capital Shares Reserved for Future Issuance Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year [Member] Research and Developement Research and Developement [Member] Research and Developement Royalty Monetizations [Line Items] Royalty Monetizations [Line Items] Royalty Monetizations Annual Net Sales Range [Axis] Annual Net Sales Range [Axis] Annual Net Sales Range Term Loan Tranche D Term Loan Tranche D [Member] Term Loan Tranche D Aggregate Erroneous Compensation Amount Aggregate Erroneous Compensation Amount Restructuring Cost and Reserve [Line Items] Restructuring Cost and Reserve [Line Items] Foreign currency gains (losses), net Gain (Loss) on Foreign Currency Derivative Instruments Not Designated as Hedging Instruments Local Phone Number Local Phone Number Annual Net Sales Under $150,000 Annual Net Sales Under $150,000 [Member] Represents annual net sales under $150,000. Aggregate Erroneous Compensation Not Yet Determined Aggregate Erroneous Compensation Not Yet Determined [Text Block] Common stock issued to directors in lieu of cash retainer Proceeds From Issuance Of Common Stock, Issued For Services Proceeds From Issuance Of Common Stock, Issued For Services Non-cash interest expense on royalty financing obligations and secured term loan and amortization of debt issuance costs Non-Cash Interest Expense On Royalty Financing Liabilities And Secured Term Loan And Amortization Of Debt Issuance Costs The amount of noncash interest expense and amortization of debt issuance costs. Expected Volatility Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate Number of securities Debt Securities, Available-for-Sale, Unrealized Loss Position, Number of Positions Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract] Changes in operating assets and liabilities: Increase (Decrease) in Operating Capital [Abstract] PEO Total Compensation Amount PEO Total Compensation Amount Long-Lived Tangible Asset [Domain] Long-Lived Tangible Asset [Domain] Income Statement Location [Axis] Statement of Income Location, Balance [Axis] Weighted average exercise price of stock option awards vested and expected to vest (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price Cash and Cash Equivalents Cash and Cash Equivalents, Policy [Policy Text Block] Maturities of investments Proceeds from Sale and Maturity of Debt Securities, Available-for-Sale Issuance of shares to directors in lieu of cash retainer Stock Issued During Period, Value, Issued for Services Debt Disclosure [Abstract] Royalty purchase agreement, royalties, percentage of sublicense revenue in other markets Royalty Purchase Agreement Royalties Percentage of Sublicense Revenue In Other Markets The percentage of sublicense revenue in other markets of royalties to be paid under the royalty purchase agreement. Common Stock Common Stock [Member] Measure: Measure [Axis] Investments [Abstract] Preferred stock, shares authorized (in shares) Preferred Stock, Shares Authorized Forgone Recovery due to Expense of Enforcement, Amount Forgone Recovery due to Expense of Enforcement, Amount Line of Credit Line of Credit [Member] Entity Emerging Growth Company Entity Emerging Growth Company Percent of interest payment Percent of Interest Payment Percent of Interest Payment Operating Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration] Operating Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration] Shares withheld for taxes for vesting of restricted stock units (in shares) Share-Based Payment Arrangement, Shares Withheld for Tax Withholding Obligation Entity Central Index Key Entity Central Index Key ORLADEYO ORLADEYO [Member] Represents ORLADEYO. Scenario [Axis] Scenario [Axis] Summary of Inventories Schedule of Inventory, Current [Table Text Block] Amortization of premium/discount on investments Amortization Of Premium/Discount On Investments Amount of amortization expense attributable to the discount and premium on investments. Non-GAAP Measure Description Non-GAAP Measure Description [Text Block] Collaborative and Other Relationships [Line Items] Research and Development Arrangement, Contract to Perform for Others [Line Items] Non-PEO NEO Average Compensation Actually Paid Amount Non-PEO NEO Average Compensation Actually Paid Amount Reclassification from accumulated other comprehensive income, current period, before tax Reclassification from Accumulated Other Comprehensive Income, Current Period, before Tax Royalty receivables from partners Royalty Receivables from Partners [Member] Information related to royalty receivables from partners. Legal Entity of Counterparty, Type [Axis] Legal Entity of Counterparty, Type [Axis] Finance lease assets, net Finance Lease, Right-of-Use Asset, after Accumulated Amortization Stockholders' Equity Equity [Text Block] Award Timing, How MNPI Considered Award Timing, How MNPI Considered [Text Block] Equity Component [Domain] Equity Component [Domain] Preferred stock par value (in usd per share) Preferred Stock, Par or Stated Value Per Share Financial Instrument [Axis] Financial Instrument [Axis] Annual Net Sales Of $2 Million Annual Net Sales Of $2 Million [Member] Annual Net Sales Of $2 Million Senior Credit Facility Senior Credit Facility [Member] Represents senior credit facility. Credit facilities provide capital to borrowers without the need to structure a loan for each borrowing. Maturity period of high quality marketable securities (in years) Maturity Period Of High Quality Marketable Securities Represents maturity period of high quality marketable securities. Additional 402(v) Disclosure Additional 402(v) Disclosure [Text Block] Periodic payment, interest Debt Instrument, Periodic Payment, Interest Stock-based compensation expense APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Entity Shell Company Entity Shell Company Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Accumulated Other Comprehensive Income Comprehensive Income, Policy [Policy Text Block] Title Trading Arrangement, Individual Title Statement [Table] Statement [Table] Interest expense, debt, total Interest Expense, Debt Counterparty Name [Axis] Counterparty Name [Axis] Significant Accounting Policies and Concentrations of Risk Significant Accounting Policies [Text Block] City Area Code City Area Code Current liabilities: Liabilities, Current [Abstract] Geographic Distribution [Domain] Geographic Distribution [Domain] Term Loan Tranche A Term Loan Tranche A [Member] Term Loan Tranche A Cash paid for interest Interest Paid, Excluding Capitalized Interest, Operating Activities Revenue Recognition Revenue [Policy Text Block] Insider Trading Policies and Procedures Not Adopted Insider Trading Policies and Procedures Not Adopted [Text Block] Acquisitions of property and equipment Payments to Acquire Productive Assets Quoted Price in Active Markets (Level 1) Fair Value, Inputs, Level 1 [Member] Stockholders' Equity Note [Abstract] Total current assets Assets, Current Statement of Cash Flows [Abstract] Statement of Cash Flows [Abstract] U.S. Geographic Distribution, Domestic [Member] Options exercisable (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number Royalties Monetizations [Table] Royalties Monetizations [Table] Royalties Monetizations Assets: Assets: Information on operating lease right-of-use assets. Long-Term Debt, Type [Axis] Schedule of Long-Term Debt Instruments [Table] Secured term loan Long-Term Debt, Excluding Current Maturities Trade Receivables Receivable [Policy Text Block] Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract] Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract] Weighted average grant date fair value stock option awards (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Restructuring Reserve [Roll Forward] Restructuring Reserve [Roll Forward] Royalty purchase agreement, royalties, percentage of annual net sales in other markets Royalty Purchase Agreement Royalties Percentage Of Annual Net Sales In Other Markets The percentage of annual net sales in other markets of royalties to be paid under the royalty purchase agreement. 2028 Lessee, Operating Lease, Liability, to be Paid, Year Four Royalty Montizations [Roll Forward] Royalty Montizations [Roll Forward] Royalty Montizations Accumulated deficit Retained Earnings (Accumulated Deficit) Finance Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration] Finance Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration] Non-cash Interest expense on Royalty financing obligations Non-Cash Interest Expense On Royalty Financing Liabilities Amount of non-cash interest expense on royalty financing obligation. Weighted average exercise price of stock option awards cancelled (in usd per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period, Weighted Average Exercise Price Inventory Increase (Decrease) in Inventories Future Royalties Payable Future Royalties Payable [Member] Represents future royalties payable. Organization, Consolidation and Presentation of Financial Statements [Abstract] Aggregate Available Trading Arrangement, Securities Aggregate Available Amount Equity Awards Adjustments Equity Awards Adjustments [Member] Operating leases Operating Lease, Weighted Average Discount Rate, Percent Total Total Operating Lease, Liability Fee amount Debt Instrument, Fee Amount Net cash (used in) provided by financing activities Net Cash Provided by (Used in) Financing Activities Underlying Securities Award Underlying Securities Amount Credit Facility [Axis] Credit Facility [Axis] Outside of U.S. Geographic Distribution, Foreign [Member] Amendment Flag Amendment Flag Entity Registrant Name Entity Registrant Name Non-cash increase to operating lease assets due to remeasurement of operating lease liabilities: Non-cash Increase In Operating Lease Assets Due To Remeasurement Of Operating Lease Liabilities Non-cash Increase In Operating Lease Assets Due To Remeasurement Of Operating Lease Liabilities Number of optional ordering periods Number of Optional Ordering Periods Number of Optional Ordering Periods Adjustment to Non-PEO NEO Compensation Footnote Adjustment to Non-PEO NEO Compensation Footnote [Text Block] Stock Appreciation Rights (SARs) Stock Appreciation Rights (SARs) [Member] Depreciation and amortization Depreciation, Depletion and Amortization Foreign currency translation adjustment Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax, Portion Attributable to Parent Fair Value as of Grant Date Award Grant Date Fair Value Amortization of right-of-use assets Finance Lease, Right-of-Use Asset, Amortization Subsequent Events [Abstract] RPI 2021 and 2020 Intermediate Finance Trust RPI 2021 and 2020 Intermediate Finance Trust [Member] Represents RPI 2021 and 2020 Intermediate Finance Trust (RPI). Selling, General and Administrative Expenses Selling, General and Administrative Expenses, Policy [Policy Text Block] Options, exercisable, aggregate intrinsic value Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value Deferred financing costs Debt Issuance Costs, Net Significant Other Observable Inputs (Level 2) Fair Value, Inputs, Level 2 [Member] Debt Debt Disclosure [Text Block] Fair Value Hierarchy and NAV [Domain] Fair Value Hierarchy and NAV [Domain] Recovery of Erroneously Awarded Compensation Disclosure [Line Items] Debt instrument, face amount Debt Instrument, Face Amount Summary of Revenues Disaggregation of Revenue [Table Text Block] OMERS Capital Markets OMERS Capital Markets [Member] Information on the rights of OMERS Capital Markets to receive certain royalty payments under the OMERS Royalty Purchase Agreement. Entity Address, Postal Zip Code Entity Address, Postal Zip Code Number of plans Share-Based Payment Arrangement, Number of Plans Share-Based Payment Arrangement, Number of Plans Schedule of Restructuring and Related Costs [Table] Restructuring Cost [Table] RPI 2019 Intermediate Finance Trust RPI 2019 Intermediate Finance Trust [Member] Represents RPI 2019 Intermediate Finance Trust (RPI).. Restatement Determination Date: Restatement Determination Date [Axis] Potential milestone payments receivable if regulatory approval before specified date Potential Milestone Payments Receivable If Regulatory Approval Before Milestone The amount of potential milestone payments receivable if regulatory approval is granted. Title of 12(b) Security Title of 12(b) Security Term Loan Tranche B Term Loan Tranche B [Member] Term Loan Tranche B Common stock, $0.01 par value; shares authorized - 450,000; shares issued and outstanding – 207,119 at September 30, 2024 and 205,771 at December 31, 2023 Common Stock, Value, Issued Doses to be delivered Number Of Product Delivered, Doses Number Of Product Delivered, Doses Significant Customers and Other Risks Concentration of Market Risk [Policy Text Block] Represents concentration of market risk policy. Contract term Contract Term Contract Term Operating cash flows for finance leases Finance Lease, Interest Payment on Liability Average maturity period of high quality marketable securities (in months) Average Maturity Period Of High Quality Marketable Securities Average maturity period of high quality marketable securities. Other Supplemental Information Related to Leases Other Supplemental Information Related to Leases [Table Text Block] Other Supplemental Information Related to Leases Accrued Interest Debt Securities, Available-for-Sale, Accrued Interest, after Allowance for Credit Loss Share-Based Payment Arrangement [Abstract] Shares issued, common stock, premium Shares Issued Common Stock Premium Information on the amount of the common stock premium. Annual Net Sales Over $230,000 Annual Net Sales Over $230,000 [Member] Represents annual net sales over $230,000. Cash and cash equivalents Cash and Cash Equivalents, at Carrying Value Laboratory Equipment, Office Equipment and Software Laboratory Equipment, Office Equipment and Software [Member] Information pertaining to laboratory equipment, office equipment and software. Certificates of deposit Certificates of Deposit [Member] Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested [Member] Debt instrument, prepayment fee, percentage of principal voluntary payments Debt Instrument Prepayment Fee Percentage of Principal Voluntary Payments The percentage of principal paid voluntarily for prepayment fee of the debt instrument. 2020 RPI Royalty Agreement 2020 RPI Royalty Agreement [Member] Information on 2020 RPI Royalty agreement. Restricted stock units, forfeited in period, weighted average grant date fair value (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Raw materials Inventory, Raw Materials, Gross Loss on extinguishment of debt Loss on extinguishment of debt Gain (Loss) on Extinguishment of Debt Cash flows from financing activities: Net Cash Provided by (Used in) Financing Activities [Abstract] Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested [Member] Preferred stock, $0.01 par value; shares authorized - 5,000; no shares issued and outstanding at September 30, 2024 and December 31, 2023 Preferred Stock, Value, Issued Investments Investments and Other Noncurrent Assets [Text Block] Finished goods Inventory, Finished Goods, Gross Property, plant and equipment, useful life (in years) Property, Plant and Equipment, Useful Life Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward] Cash and Cash Equivalents [Domain] Cash and Cash Equivalents [Domain] Basic net loss per common share (in usd per share) Earnings Per Share, Basic Receivables Billing Status [Domain] Receivables Billing Status [Domain] Accounts payable and accrued expenses Increase (Decrease) in Accounts Payable Operating cash flows for operating leases Operating Lease, Payments Adjustment To PEO Compensation, Footnote Adjustment To PEO Compensation, Footnote [Text Block] Award Timing MNPI Disclosure Award Timing MNPI Disclosure [Text Block] Upfront payment License Agreement, Upfront Payment License Agreement, Upfront Payment Principal payments on finance lease liabilities Financing cash flows for finance leases Finance Lease, Principal Payments Royalty purchase agreement, royalties, percentage of annual net sales in key territories Royalty Purchase Agreement Royalties Percentage Of Annual Net Sales In Key Territories The percentage of net sales in key territories for royalties to be paid under the royalty purchase agreement. Aggregate Pension Adjustments Service Cost Aggregate Pension Adjustments Service Cost [Member] Royalty financing obligations Royalty Financing Liabilities, Noncurrent Carrying amount as of the balance sheet date of obligations for future royalties. Property and Equipment Property, Plant and Equipment, Policy [Policy Text Block] Compensation Actually Paid vs. Other Measure Compensation Actually Paid vs. Other Measure [Text Block] Total current liabilities Liabilities, Current Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year [Member] Total assets Assets Cost of product sales Cost of Goods and Services Sold Issued RSU (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period Total inventory, net Inventory, Including Noncurrent Portion Inventory, Including Noncurrent Portion Forgone Recovery due to Violation of Home Country Law, Amount Forgone Recovery due to Violation of Home Country Law, Amount Stock-Based Compensation Share-Based Payment Arrangement [Policy Text Block] Annual Net Sales Greater Than $1.5 Million Annual Net Sales Greater Than $1.5 Million [Member] Annual Net Sales Greater Than $1.5 Million Termination Date Trading Arrangement Termination Date 2026 Lessee, Operating Lease, Liability, to be Paid, Year Two Share-Based Compensation Share-Based Payment Arrangement [Text Block] Potential milestone payment Potential Milestone Payments Payable Potential Milestone Payments Payable Royalty purchase agreement, royalties, maximum tiered profit share percentage on permitted sales in other markets Royalty Purchase Agreement Royalties Maximum Tiered Profit Share Percentage On Permitted Sales In Other Markets The percentage of net sales in certain markets for royalties to be paid under the royalty purchase agreement. Entity Address, City or Town Entity Address, City or Town Net proceeds from Pharmakon Tranche A term loan Proceeds from Issuance of Long-Term Debt Proceeds from collaborators Proceeds from Collaborators Debt Covenant Terms [Domain] Debt Covenant Terms [Domain] Debt Covenant Terms Leases Lessee, Leases [Policy Text Block] Issuance of shares to directors in lieu of cash retainer (in shares) Stock Issued During Period, Shares, Issued for Services Debt Instrument [Axis] Debt Instrument [Axis] Weighted average remaining contractual life Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value Schedule of Royalty Financing Obligations Royalty Financing Liabilities [Table Text Block] Tabular disclosure for royalty financing obligations. Stock-based compensation expense Share-Based Payment Arrangement, Expense Net loss Net loss Net Income (Loss) Attributable to Parent Trading Arrangement: Trading Arrangement [Axis] Revenues Revenue from Contract with Customer, Including Assessed Tax Weighted average exercise price of stock option awards granted (in usd per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Pay vs Performance Disclosure, Table Pay vs Performance [Table Text Block] Forfeited RSU (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period Equity Awards Adjustments, Excluding Value Reported in Compensation Table Equity Awards Adjustments, Excluding Value Reported in the Compensation Table [Member] Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year [Member] Entity File Number Entity File Number Finance Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract] Finance Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract] Debt Securities, Available-for-Sale, Accrued Interest, after Allowance for Credit Loss, Statement of Financial Position [Extensible Enumeration] Debt Securities, Available-for-Sale, Accrued Interest, after Allowance for Credit Loss, Statement of Financial Position [Extensible Enumeration] Revenue Revenue from Contract with Customer [Text Block] Document Fiscal Year Focus Document Fiscal Year Focus Income Statement [Abstract] Income Statement [Abstract] Entity Address, Address Line One Entity Address, Address Line One Significant Accounting Policies and Concentration of Risk [Line Items] Significant Accounting Policies and Concentrations of Risk [Line Items] Significant Accounting Policies and Concentrations of Risk Retirement Policy Retirement Policy [Member] Retirement Policy Debt Instrument, Name [Domain] Debt Instrument, Name [Domain] Effect of exchange rate on cash, cash equivalents, and restricted cash Effect of Exchange Rate on Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Continuing Operations Lessee, operating lease, term of contract (in years) Lessee, Operating Lease, Term of Contract Name Forgone Recovery, Individual Name Stock option awards vested and expected to vest, weighted average remaining contractual life (year) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value 2024 (remaining) Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year Loan Agreement Loan Agreement [Member] Loan Agreement Weighted average remaining lease term (in years) Operating Lease, Weighted Average Remaining Lease Term Document Period End Date Document Period End Date Reserves Inventory Valuation Reserves Finance lease liabilities Finance Lease, Liability, Current Investments Investment, Policy [Policy Text Block] Award Timing MNPI Considered Award Timing MNPI Considered [Flag] Total lease payments Lessee, Operating Lease, Liability, to be Paid Unvested RSU beginning balance (in shares) Unvested RSU ending balance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number Line of Credit Facility, Lender [Domain] Line of Credit Facility, Lender [Domain] Insider Trading Arrangements [Line Items] Debt Covenant Terms [Axis] Debt Covenant Terms [Axis] Debt Covenant Terms Inventory Disclosure [Abstract] Outstanding Aggregate Erroneous Compensation Amount Outstanding Aggregate Erroneous Compensation Amount Schedule of Stock by Class Schedule of Stock by Class [Table Text Block] Royalty financing obligations Royalty Financing Liabilities, Current Royalty Financing Liabilities, Current Accrued Expenses Accrued Expenses [Policy Text Block] Represents accrued expenses policy. 2027 Lessee, Operating Lease, Liability, to be Paid, Year Three PEO Actually Paid Compensation Amount PEO Actually Paid Compensation Amount Royalty revenues paid and payable Royalty Revenues Paid And Payable Represents royalties revenues paid and payable. Adjustment to Compensation: Adjustment to Compensation [Axis] Prepaid expenses and other current assets Prepaid Expense and Other Assets, Current Equity Disclosure [Table] Subsidiary or Equity Method Investee, Sale of Stock, Type [Table] Birmingham lease restricted cash Restricted Cash and Cash Equivalents, Noncurrent Document Transition Report Document Transition Report Document Quarterly Report Document Quarterly Report Accumulated other comprehensive income Accumulated Other Comprehensive Income (Loss), Net of Tax Entity Current Reporting Status Entity Current Reporting Status Accumulated Deficit Retained Earnings [Member] Restricted cash Restricted Cash and Cash Equivalents Amortization of debt issuance costs Amortization of Debt Issuance Costs Prepayment and repayment fees on Athyrium secured term loans Payments of Loan Costs Pension Adjustments Service Cost Pension Adjustments Service Cost [Member] Annual Net Sales Under $1.5 Million Annual Net Sales Under $1.5 Billion [Member] Represents annual net sales under $1.5 billions. Weighted average shares outstanding, basic (in shares) Weighted Average Number of Shares Outstanding, Basic Stock Price or TSR Estimation Method Stock Price or TSR Estimation Method [Text Block] Marketable Securities [Line Items] Marketable Securities [Line Items] Long-term inventory, net Inventory, Noncurrent Equity Disclosure [Line Items] Subsidiary, Sale of Stock [Line Items] Unvested restricted stock unit awards Restricted Stock Units (RSUs) [Member] Increase (Decrease) in Stockholders' Equity [Roll Forward] Increase (Decrease) in Stockholders' Equity [Roll Forward] Executive Category: Executive Category [Axis] Name Awards Close in Time to MNPI Disclosures, Individual Name London Interbank Offered Rate (LIBOR) London Interbank Offered Rate [Member] London Interbank Offered Rate Credit Agreement Credit Agreement [Member] Represents the credit agreement. Entity Filer Category Entity Filer Category Restructuring reserve Restructuring costs, beginning balance Restructuring costs, ending balance Restructuring Reserve Royalty rate Royalty Rate Royalty Rate Income Statement Location [Domain] Statement of Income Location, Balance [Domain] Between the Second and Third Anniversaries Between the Second and Third Anniversaries [Member] Represents between the second and third anniversaries. Purchase of investments Payments to Acquire Debt Securities, Available-for-Sale Company Selected Measure Name Company Selected Measure Name