SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person* ALEXANDER W JAMES (Last) (First) (Middle) 2190 PARKWAY LAKE DRIVE (Street) BIRMINGHAM AL 35244- (City) (State) (Zip)	2. Date of Event Requiring Statement (Month/Day/Year) 06/19/2006	3. Issuer Name and Ticker or Trading Symbol BIOCRYST PHARMACEUTICALS INC [ BCRX ]
		4. Relationship of Reporting Person(s) to Issuer (Check all applicable) Director 10% Owner X Officer (give title below) Other (specify below) SR. VP, Chief Medical Officer	5. If Amendment, Date of Original Filed (Month/Day/Year)
			6. Individual or Joint/Group Filing (Check Applicable Line) X Form filed by One Reporting Person Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

No securities are beneficially owned.

	Michael Richardson by Power of Attorney	06/21/2006
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
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POWER OF ATTORNEY

Know all men by these presents, that the undersigned director whose signature
appears
below hereby constitutes and appoints Michael A. Darwin and Michael
Richardson, and
each of them, his true and lawful attorneys-in-fact and agents, with full
power of
substitution and resubstitution, for him and in his name, place and stead,
in any
and all capacities:

To execute for and on behalf of the undersigned Forms 3, 4, 5, Schedule
13D and
amendments thereto in accordance with Sections 13(d) and 16(a) of the
Securities
Exchange Act of 1934 and the rules thereunder;

i)	To do and perform any and all acts for and on behalf of the
undersigned
which may be necessary or desirable to complete the execution of any such Form
 3, 4,
 5 or Schedule 13D and the timely filing of such form with the United States
Securities
 and Exchange Commission and any other authority; and

ii)	To take any other action of any type whatsoever in connection with
the
foregoing which, in the opinion of such attorneys-in-fact, may be of benefit
to,
in the best interest of, or legally required by, the undersigned, it being
understood
that the documents executed by such attorneys-in-fact on behalf of the
undersigned
pursuant to this Power of Attorney shall be in such form and shall contain
such terms
and conditions as such attorneys-in-fact may approve in his discretion.

The undersigned hereby grants to such attorneys-in-fact and agents full power
 and
authority to do and perform all and every act and thing whatsoever requisite,
necessary and proper to be done in the exercise of any of the rights and
powers
herein granted, as fully to all intents and purposes as the undersigned
might or
could do if personally present, with full power of substitution or revocation,
hereby ratifying and confirming all that such attorney-in-fact, or his
substitute
or substitutes, shall lawfully do or cause to be done by virtue of this Power
 of
Attorney and the rights and powers herein granted. The undersigned acknowledges
that the foregoing attorneys-in-fact,in serving in such capacity at the request
 of
the undersigned, is not assuming any of the undersigned's responsibilities to
comply
 with Sections 13(d) and 16 of the Securities Exchange Act of 1934.

IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney as of
this
 ___19th day of ___June______, 2006.


_____________
Jim Alexander